Studies on the toxicity of beechwood creosote (3) Chronic toxicity and carcinogenicity in rats

Miyazato T., Suzuki A., Uenishi C., Yamanaka K. Oyo Yakuri 28, 925-947 (1984).

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山毛櫸木餾油對於實驗鼠的慢性毒性與致癌性實驗

Studies on the toxicity of beechwood creosote (2) Chronic toxicity and carcinogenicity in mice

Miyazato T., Matsumoto M., Nohno M., Yamanaka K. Oyo Yakuri 28, 909-924 (1984).

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山毛櫸木餾油對於一般老鼠的慢性毒性與致癌性實驗

Wood creosote, the principal active ingredient of Seirogan, an herbal antidiarrheal medicine: a single-dose, dose-escalation safety and pharmacokinetic study

Kuge T., Shibata T., Willett M. S. Pharmacotherapy 23, 1391-1400 (2003).

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對健康受測者單次投予複數用量時的正露丸主成分之木餾油的安全性與藥力學實驗

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Multiple-dose escalation, safety, and tolerability study of wood creosote, the principal active ingredient of Seirogan, an herbal antidiarrheal medication, in healthy subjects

Kuge T., Shibata T., Willett M. S. J Clin Pharmacol 43, 284-290 (2003).

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對健康受測者多次投予複數用量時的正露丸主成分之木餾油的安全性與耐藥性實驗

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Stress-induced breakdown of intestinal barrier function in the rat: reversal by wood creosote

Kuge T., Greenwood-Van Meerveld B., Sokabe M. Life Sci 79, 913-918 (2006).

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壓力誘發之消化器官膈膜崩毀:使用木餾油令其恢復

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Inhibition of rat intestinal Cl- secretion by 4,5-dimethylresorcinol

Ogata N., Shibata T. Pharmacology 72, 247-253 (2004).

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4,5-以乙烷間苯二酚(Dimethyl resorcinol)阻礙實驗鼠的腸道分泌氯離子

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Wood creosote inhibits calcium mobilization in guinea pig colonic smooth muscle

Morino H., Ataka K., Ito M., Kuge T. Biol Pharm Bull 27, 1046-1051 (2004).

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以木餾油阻礙土撥鼠的結腸平滑肌內鈣質活動

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Seirogan (wood creosote) inhibits stress-induced ion secretion in rat intestinal epithelium

Ataka K., Kuge T., Venkova K., Greenwood-Van Meerveld B. Dig Dis Sci 48, 1303-1309 (2003).

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以正露丸（木餾油）抑制壓力誘發之實驗鼠消化器官上皮的離子分泌動作

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Effects of Seirogan (wood creosote) on propulsive colonic motility and stool characteristics in ambulatory mini-pigs

Kuge T., Venkova K., Greenwood-Van Meerveld B. Dig Dis Sci 47, 2651-2656 (2002).

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正露丸(木餾油)對在未拘束狀態下之迷你豬的大腸蠕動運動與大便特性(硬度)的影響

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In vitro effects of wood creosote on enterotoxin-induced secretion measured
electrophysiologically in the rat jejunum and colon

Kuge T., Venkova K., Greenwood-Van Meerveld B. Biol Pharm Bull 24, 623-627 (2001).

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以電子生理學方式測得之木餾油對實驗鼠空腸與結腸中之In vitro的腸毒素誘發性分泌的影響

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Antidiarrheal activity of wood creosote: inhibition of muscle contraction and enterotoxin-induced fluid secretion in rabbit small intestine

Ogata N., Shibata T. Pharmacology 62, 181-187 (2001).

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木餾油的止瀉活性：對兔子小腸中的肌肉收縮動作與腸毒素誘發性腸液分泌動作的抑制效果

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Comparison of the antidiarrheal effects of wood creosote and loperamide in the rat jejunum and colon in vitro

Greenwood-Van Meerveld B., Tyler K. R., Venkova K., Kuge T. Biol Pharm Bull 23, 952-956 (2000).

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木餾油與樂必寧對In vitro的實驗鼠空腸與結腸的止瀉效果比較

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Effect of wood creosote and loperamide on propulsive motility of mouse colon and small intestine

Ogata N., Ataka K., Morino H., Shibata T. Pharmacology 59, 212-220 (1999).

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木餾油與樂必寧對於老鼠結腸與小腸推進運動性的影響

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Anti-diarrhoeal effects of Seirogan in the rat small intestine and colon examined in vitro

Greenwood-Van Meerveld B., Tyler K., Kuge T., Ogata N. Aliment Pharmacol Ther 13, 97-102 (1999).

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正露丸對In vitro的實驗鼠空腸與結腸的止瀉效果

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Inhibitory effect of creosote and its main components on production of verotoxin of enterohaemorrhagic Escherichia coli O157:H7

Sakagami Y., Ichise R., Kajimura K., Yokoyama H. Lett Appl Microbiol 28, 118-120 (1999).

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木餾油與其主要成分對於腸出血性大腸菌O157:H7 Vero素產生情況抑制效果

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Effects of wood creosote on vero toxin-induced damage to rabbit jejunum

Shibata T., Ogata N. J New Remedies & Clinics 47, 765-771 (1998).

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木餾油對於Vero毒素的腸道黏膜症狀功效

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Suppression of enterotoxin-induced intestinal fluid secretion by wood creosote

Ataka K., Ogata N., Kuge T., Shibata T. Res Commun Mol Pathol Pharmacol 93, 219-224 (1996).

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木餾油對腸毒素誘發性腸液分泌的抑制效果

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Suppression of intestinal smooth muscle contraction by 4-ethylguaiacol, a constituent of wood creosote

Toyoda M., Ogata N., Shibata T. Pharmacology 47, 300-308 (1993).

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木餾油的成分4-乙基癒創木酚抑制腸道平滑肌收縮的效果

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Demonstration of antidiarrheal and antimotility effects of wood creosote

Ogata N., Baba T., Shibata T. Pharmacology 46, 173-180 (1993).

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木餾油的止瀉效果與運動抑制效果的實證

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Citri Unshiu Pericarpium prolongs mean residence time of guaiacol after oral administration of wood creosote pill to rats

Baba T., NishinoT., Tani T. J Trad Med 21, 137-142 (2004).

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陳皮粉末可在經由口服方式對實驗鼠投予木餾油後，延長癒創木酚的平均滯留時間

Denaturation of protein by chlorine dioxide: oxidative modification of tryptophan and tyrosine residues

Ogata N. Biochemistry 46, 4898-4911 (2007).

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蛋白質因二氧化氯產生的性質變異:色氨酸與酪氨酸殘基的氧化性修飾

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Origin of genomic DNA: discussion from reverse-transcription and expansion of repetitive oligonucleotides

Miura T. Viva Origino 31, 46-61 (2003).

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基因組DNA的起源:由短鏈反覆核酸的逆轉寫與延長合成的關察結果

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Elongation of tandem repetitive DNA by the DNA polymerase of the hyperthermophilic archaeon Thermococcus litoralis at a hairpin-coil transitional state: a model of amplification of a primordial simple DNA sequence

Ogata N., Miura T. Biochemistry 39, 13993-14001 (2000).

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高度嗜熱性古細菌Thermococcus litoralis的DNA聚合脢造成的髮夾-線圈遷移狀態下的反覆DNA延長：原始純粹DNA排列的增幅模型

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Creation of genetic information by DNA polymerase of the thermophilic bacterium Thermus thermophilus

Ogata N., Miura T. Nucleic Acids Res 26, 4657-4661 (1998).

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嗜熱性細菌Thermus thermophilus的DNA聚合脢引發的遺傳資訊創造動作

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Creation of genetic information by DNA polymerase of the archaeon Thermococcus litoralis: influences of temperature and ionic strength

Ogata N., Miura T. Nucleic Acids Res 26, 4652-4656 (1998).

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古細菌 Thermococcus litoralis的DNA聚合脢引發的遺傳資訊創造動作:溫度與離子強度的影響

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